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Fig. 2 | Acta Epileptologica

Fig. 2

From: Heterogeneity of clinical features, EEG and brain imaging findings in anti-leucine-rich glioma-inactivated protein 1 autoimmune encephalitis: a retrospective case series study and review of the literature

Fig. 2

a The case #6 developed asymmetric hippocampal atrophy as seen in serial brain MRI images. b Fulminant cerebral edema seen in case #5, more in the left hemisphere. c Brain PET revealed hypermetabolism in the basal ganglion in case #2 with FBDS. d The case #8 showed bilateral hypometabolism in the frontal and temporal lobes with rapid neurocognitive decline (brain PDG-PET scan); biodistribution shows statistically significant hypometabolism with very low Z-scores (-3, shown as purple-blue pseudo-color) in the posterior cingulate gyrus, as well as frontal (left worse than right) and temporal lobes (right worse than left). Upper panel shows the spatial structural localization of the hypometabolism; lower panel shows the fusion of images with low structural resolution to highlight the affected brain regions

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