Articles

Interictal and Ictal MEG in presurgical evaluation for epilepsy surgery

Although presurgical evaluation of patients with pharamacoresistent focal epilepsies provides essential information for successful epilepsy surgery, there is still a need for further improvement. Developments ...

Authors: Hermann Stefan and Stefan Rampp

Continuous video electroencephalogram for herpes simplex encephalitis: a case report and literature review

Electroencephalogram (EEG) is an important tool for the diagnosis of herpes simplex virus encephalitis (HSE). However, the diagnosis of non-convulsive status epilepticus (NCSE) in HSE is challenging without th...

Authors: Wanhui Lin, Shenggen Chen, Hanbin Lin, Changyun Liu and Huapin Huang

Electromagnetic activity: a possible player in epilepsy

Epilepsy is a common disease with frequent occurrences. Many precipitating factors contribute to epileptic seizures, such as hyperventilation and alcohol consumption. An increasing number of studies have also ...

Authors: Yi Guo, Yaowen Liu and Xuefeng Wang

Expert consensus on clinical applications of high-frequency oscillations in epilepsy

Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs c...

Authors: Yuping Wang, Dong Zhou, Xiaofeng Yang, Xin Xu, Liankun Ren, Tao Yu, Wenjing Zhou, Xiaoqiu Shao, Zhixian Yang, Shuang Wang, Dezhi Cao, Chunyan Liu, Shang Yeong Kwan and Jing Xiang

The first-line management of psychogenic non-epileptic seizures (PNES) in adults in the emergency: a practical approach

Distinguishing non-epileptic events, especially psychogenic non-epileptic seizures (PNES), from epileptic seizures (ES) constitutes a diagnostic challenge. Misdiagnoses are frequent, especially when video-EEG ...

Authors: Dènahin Hinnoutondji Toffa, Laurence Poirier and Dang Khoa Nguyen

Epilepsy control during an epidemic: emerging approaches and a new management framework

Epidemics are a big threat to world health. The ongoing pandemic of corona virus disease 2019 (COVID-19) has caused a series of challenges to public health. One such challenge is the management of chronic dise...

Authors: Deng Chen, Lina Zhu, Xin Lin, Zhen Hong, Shichuo Li, Ling Liu and Dong Zhou

Machine learning applications for electroencephalograph signals in epilepsy: a quick review

Machine learning (ML) is a fundamental concept in the field of state-of-the-art artificial intelligence (AI). Over the past two decades, it has evolved rapidly and been employed wildly in many fields. In medic...

Authors: Yang Si

The ketogenic diet for paediatric patients with super-refractory status epilepticus in febrile infection-related epilepsy syndrome

To investigate the effect and safety of ketogenic diet (KD) for the treatment of paediatric patients with super-refractory status epilepticus (SRSE) in febrile infection-related epilepsy syndrome (FIRES).

Authors: Xinhua Wang, Xuan Gao, Guoping Lu, Zhongying Lu, Shuizhen Zhou, Yi Wang and Yuanfeng Zhou

A case report of microcephaly and refractory West syndrome associated with WDR62 mutation

The autosomal recessive form of primary microcephaly (MCPH) is a rare disorder characterized by microcephaly with variable degree of intellectual disability. WDR62 has been reported as the second causative gene o...

Authors: Ping Zhou, Xin Ding, Qi Zeng, Huafang Zou, Jianxiang Liao and Dezhi Cao

The clinical phenotypes and genetic characteristics of seven epilepsy patients related to heterozygous DEPDC5 variants in China

DEPDC5 together with NPRL2 and NPRL3 forms the GATOR1 which plays an important role in the the mechanistic target of rapamycin (mTOR) pathway. Deregulation of mTOR signalling has been associated to various neu...

Authors: Zihan Wei, Luojun Wang, Xiaozhi Qiao, Ying Zhang, Chao Liu and Yanchun Deng

The prevalence, characteristics and outcome of seizure in tuberculous meningitis

Seizures are a common finding in patients with tuberculous meningitis (TBM), and associate with four times increased risk of death and neurological disability, especially in children. It has been reported that...

Authors: Ammar Taha Abdullah Abdulaziz, Jinmei Li and Dong Zhou

Correction to: Ictal semiology, functional anatomy and multimodal diagnostic in patients with insular epilepsies

After publication of this article [1], it is noticed there are errors with figure numbering and matching between figure artwork and caption with Figs. 3, 4, 5 and 6.

Authors: Hermann Stefan and Stephanie Gollwitzer

Ictal semiology, functional anatomy and multimodal diagnostic in patients with insular epilepsies

The insula is a hidden part in the cerebral cortex. Insular epilepsy is underrecognized and it bears a special risk for misdiagnosis with regard to nonepileptic seizures or wrong localization of epileptic seiz...

Authors: Hermann Stefan and Stephanie Gollwitzer

A clinical and pathological study in patients with sudden unexpected death in Epilepsy

Sudden unexpected death of epilepsy (SUDEP) is a severe outcome of epilepsy. This study aimed to report the clinical and pathological findings in patients with SUDEP.

Authors: Weihua Yu, Ying Zhu, Qingshu Li, Xin Tian, Peng Zhang and Yang Lü

Differential diagnosis between epileptic seizures and psychogenic nonepileptic seizures based on semiology

Psychogenic nonepileptic seizures present as paroxysmal symptoms and signs mimicking epileptic seizures. The gold standard test is the synchronous recording by video, electrocardiogram and electroencephalogram...

Authors: Xiaohui Xiang, Jiajia Fang and Yi Guo

Cases with parietal and occipital lobe epilepsies

For seizures emerging from the posterior cortex it can be a challenge to differentiate if they belong to temporal, parietal or occipital epilepsies. Sensoric auras like visual phenomena may occur in all of the...

Authors: Hermann Stefan

SiRNA-mediated ankyrin-G silence modulates the expression of voltage-gated Na channels in murine hippocampal HT22 cells

Voltage-gated sodium channels are the targets of many commonly used antiepileptic drugs. Na_V1.6, encoded by Scn8a, increased in chronic mesial temporal epilepsy animal models and co-localized with Ankyrin-G, enco...

Authors: Guanzhong Ni, Xiaoting Hao, Xiaodong Cai, Jiaming Qin, Liemin Zhou, Patrick Kwan and Ziyi Chen

Strategies for epilepsy control in public health aspects

This article provides the authors’ recommendations of strategies for epilepsy control in public health aspects. Besides a brief review of some collaborative epilepsy control activities in public health aspects...

Authors: Shichuo Li, Ding Ding and Xiaoyan Liu

Systemic evidence of acute seizure-associated elevation in serum neuronal injury biomarker in patients with temporal lobe epilepsy

Patients with drug refractory temporal lobe epilepsy frequently accumulate cognitive impairment over time, suggesting loss of neurons induced by seizures. Our objective was to determine whether there is a temp...

Authors: Shailaja Kunda, Reghann G. LaFrance-Corey, Fatemeh Khadjevand, Gregory A. Worrell and Charles L. Howe

Acta Epileptologica: for sharing research advances in epilepsy research

Authors: Shichuo Li