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  1. Early diagnosis of medically intractable epilepsy is challenging in clinical work. P-glycoprotein (P-gp) is one of the most important multidrug efflux transporters, which has been demonstrated to contribute to...

    Authors: Yangmei Xie, Yiye Shao, Xue Gong, Ming Wang and Yinghui Chen
    Citation: Acta Epileptologica 2023 5:5
    Content type: Research Published on:

  2. Reflex seizures (RS) induced by micturition are extremely rare, and the clinical and electroencephalogram features of RS are not widely known among clinicians. In particular, the origin of the epileptic area i...

    Authors: Zhiyun Zhang, Qiwei Li, Tiejia Jiang and Jiajia Fang
    Citation: Acta Epileptologica 2023 5:4
    Content type: Case Report Published on:

  3. We have previously reported that hippocampal long-term potentiation (LTP) was suppressed in temporal lobe epilepsy (TLE) rats. The N-methyl-D-aspartic acid receptors containing 2B subunit (NR2B-NMDARs) are ind...

    Authors: Xiaoqing Luo, Cheng Li, Xiaoli Yu, Guangtao Kuang, Xiaolu Wang, Jufang Liang and Jun Jiang
    Citation: Acta Epileptologica 2023 5:1
    Content type: Research Published on:

  4. Lennox-gastaut syndrome (LGS) is an epileptic encephalopathy often associated with behavioral and psychiatric disorders. Vagus nerve stimulation (VNS) has been approved effective for LGS treatment. Surgical re...

    Authors: Renli Qi, Wei Wang, Yaoduan Xu, Zongling Shen, Xin Geng, Na Li, Jinghui Li and Hualin Yu
    Citation: Acta Epileptologica 2022 4:40
    Content type: Case Report Published on:

  5. Recent studies suggest potential roles of immune response in the pathophysiology of epilepsy. Anti-seizure medications (ASMs) are known to have side effects of drug eruption caused by immune responses. A few r...

    Authors: Takuji Nakamura, Keiko Uda, Muneaki Matsuo and Masafumi Zaitsu
    Citation: Acta Epileptologica 2022 4:36
    Content type: Case Report Published on:

  6. The KCNT1 gene encodes a Na+-activated K+ channel. Gain-of-function mutations of KCNT1 lead to autosomal dominant sleep-related hypermotor epilepsy, early-onset epileptic encephalopathy, focal epilepsy and other ...

    Authors: Meng Wang, Guifu Geng, Yao Meng, Hongwei Zhang, Zaifen Gao and Jianguo Shi
    Citation: Acta Epileptologica 2022 4:34
    Content type: Case Report Published on:

  8. Epilepsy affects over 70 million people worldwide; however, the underlying mechanisms remain unclear. MicroRNAs (miRNAs) have essential functions in epilepsy. miRNA-9, a brain-specific/enriched miRNA, plays a ...

    Authors: Shenglin Wang, Xuzhi He, Nana Bao, Mingyue Chen, Xiaomi Ding, Ming Zhang, Li Zhao, Shunxian Wang and Guohui Jiang
    Citation: Acta Epileptologica 2022 4:33
    Content type: Research Published on:

  9. Brain function is thought to rely on complex interactions of dynamic neural systems, which depend on the integrity of structural and functional networks. Focal epilepsy is considered to result from excessive f...

    Authors: Yanping Sun, Yuqiang Song, Hongjin Ren, Haifang Zhu, Yanning Wang, Xiaoli Li, Wenjing Yan and Yuping Wang
    Citation: Acta Epileptologica 2022 4:42
    Content type: Research Published on:

  10. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis accounts for the vast majority of cases of autoimmune encephalitis. Its common clinical symptoms are psychiatric symptoms, behavioral dysfunction, seizures,...

    Authors: Junjie Hu, Cailei Zhao, Xia Zhao, Yu Fang, Huiting Zhang, Dezhi Cao and Jianxiang Liao
    Citation: Acta Epileptologica 2022 4:30
    Content type: Case Report Published on:

  12. Posterior quadrant epilepsy (PCE) is a type of focal epilepsy that originates in the parietal lobe, occipital lobe, and the parietal-occipital border of the temporal lobe, or in any combination of these region...

    Authors: Mario Velasco, Andrés Felipe Cárdenas-Cruz, María Paula Aguilera-Pena, Alejandro Vargas-Moreno, Daniel Nariño, Juan Carlos Pérez and Oscar Zorro
    Citation: Acta Epileptologica 2022 4:27
    Content type: Research Published on:

  14. Vagus nerve stimulation (VNS) is an effective treatment for patients with refractory epilepsy, yet with varied predictive factors and heterogeneous long-term outcomes. Adjustment of VNS parameters is critical ...

    Authors: Cuiping Xu, Hua Lin, Jiwen Xu, Xiaohua Zhang, Guiliang Hao, Qiang Qiang Liu, Chengyun Ding, Shan Wang, Quanjun Zhao, Xiaojun Bai, Kui Chen, Duanyu Ni, Yongjie Li, Tao Yu and Yuping Wang
    Citation: Acta Epileptologica 2022 4:38
    Content type: Research Published on:

  16. Dravet syndrome (DS) is a severe epileptic encephalopathy in children dominated by polymorphic seizures. Focal cortical myoclonus indicated on conventional electroencephalogram (EEG) was rarely observed in DS.

    Authors: Xiaoqing Luo, Xiaolu Wang and Jun Jiang
    Citation: Acta Epileptologica 2022 4:13
    Content type: Case Report Published on:

  17. Evidence about the interaction between circadian rhythms (CR) and epilepsy has been expanded with the application of advanced detection technology. An adequate understanding of how circadian system and epileps...

    Authors: Mingsu Liu, Jing Ding and Xin Wang
    Citation: Acta Epileptologica 2022 4:28
    Content type: Review Published on:

  18. Juvenile myoclonic epilepsy (JME) is the most common syndrome of idiopathic generalized epilepsy. Although resting-state functional magnetic resonance imaging (rs-fMRI) studies have found thalamocortical circu...

    Authors: Linyuan Qin, Yingying Zhang, Jiechuan Ren, Du Lei, Xiuli Li, Tianhua Yang, Qiyong Gong and Dong Zhou
    Citation: Acta Epileptologica 2022 4:29
    Content type: Research Published on:

  19. Temporal lobe epilepsy (TLE) is difficult to treat as it is often refractory to treatment. Apart from traditional medical treatment, surgical resection is also a choice of treatment, but it may be associated w...

    Authors: Ashabilan Abdikarim Ebrahim and Alexander Tungu
    Citation: Acta Epileptologica 2022 4:25
    Content type: Review Published on:

  20. Malformation of cortical development (MCD) is a common cause of intractable epilepsy in children. In this study, the effectiveness of frontal lobe epilepsy (FLE) surgery in children with intractable epilepsy d...

    Authors: Hao Yu, Qiang Lv, Qingzhu Liu, Shuang Wang, Taoyun Ji, Ruofan Wang, Wen Wang, Dongming Wang, Yuwu Jiang, Xiaoyan Liu and Lixin Cai
    Citation: Acta Epileptologica 2022 4:23
    Content type: Research Published on:

  23. Status epilepticus (SE) is a neurological emergency associated with high mortality and morbidity. Many SE episodes cannot be quickly and effectively terminated with current medications. miRNA-Let-7i, a member ...

    Authors: Shu Ou, Xi Liu, Tao Xu, Xinyuan Yu, Teng Wang, Yangmei Chen and Haiyan Luo
    Citation: Acta Epileptologica 2022 4:20
    Content type: Research Published on:

  25. The lack of social support for adults with epilepsy (AWEs) is receiving increased attention, as it may result in low quality of life. This study was aimed to confirm the demographic characteristics of and clin...

    Authors: Rui Zhong, Hanyu Zhang, Yujuan Han, Xin Guo and Weihong Lin
    Citation: Acta Epileptologica 2022 4:18
    Content type: Research Published on:

  26. Epilepsy is a paroxysmal disorder of the brain, caused by an imbalance of neuronal excitation and inhibition. Glutamate is the most important excitatory neurotransmitter in the brain and plays an important rol...

    Authors: Yan Feng, Cuirong Zhang, Zihan Wei, Guoyan Li, Yajing Gan, Chao Liu and Yanchun Deng
    Citation: Acta Epileptologica 2022 4:31
    Content type: Research Published on:

  27. The aim of this review is to (a) characterize social cognition impairments in the domains of emotion recognition (ER) and theory of mind (ToM) in patients with epilepsy and (b) to review assessment tools with ...

    Authors: Marcel Eicher and Hennric Jokeit
    Citation: Acta Epileptologica 2022 4:24
    Content type: Research Published on:

  29. Whether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was aimed to evaluate whether HHV-6B is significantly associated with MTLE.

    Authors: Jingyi Tong, Qin Zou, Sheng Wang, Jiaqi Liu, Rong Chen, Yongmin Chen, Wenjie Zhao, Lin Ma and Qifu Li
    Citation: Acta Epileptologica 2022 4:19
    Content type: Research Published on:

  30. Inflammation plays an important role in the pathogenesis of status epilepticus (SE). The long non-coding RNA (lncRNA) taurine up-regulated gene1 (Tug1) plays a well-defined role in inflammatory diseases. Howev...

    Authors: Ming Wang, Yangmei Xie, Yiye Shao and Yinghui Chen
    Citation: Acta Epileptologica 2022 4:9
    Content type: Research Published on:

  31. This study was aimed to investigate whether patients with epilepsy (PWE) have higher depression and anxiety levels than the normal population in low-risk areas for coronavirus disease 2019 (COVID-19) in the no...

    Authors: Shen Wang, Juan Yang, Nian Wei, Wenbo Lv, Zhigang Jiang, Hao Huang, Jun Zhang, Ping Xu, Chang Yin Yu and Zucai Xu
    Citation: Acta Epileptologica 2022 4:22
    Content type: Research Published on:

  35. The nonconvulsive status epilepticus (NCSE) is an epileptic condition characterized by little or no obvious symptoms, thus is often easily to be underrecognized, underdiagnosed or even undetected by clinicians...

    Authors: Dan Wu, Xiaoyun Liu, Xingqi Yao, Yanfeng Yang, Jun Zhang, Haoran Yang and Wei Sun
    Citation: Acta Epileptologica 2022 4:4
    Content type: Case Report Published on:

  38. Due to the tradition of carbohydrate-rich diet, challenges exist for ketogenic diet (KD) implementation in Northwest China. This study was aimed to investigate the efficacy and tolerability of KD therapy admin...

    Authors: Xiangjun Dou, Zhijing Wang, Xia Li, Yan Wang, Shanshan Jia, Xixiao Song and Dong Wang
    Citation: Acta Epileptologica 2022 4:10
    Content type: Research Published on:

  39. West syndrome is a devastating disorder characterized by a triad of epileptic spasms, abnormal electroencephalography (EEG), and developmental arrest or psychomotor delay. In addition to early diagnosis, knowi...

    Authors: Han Wang, Yanwei Zhu, Dezhi Cao, Hong Chen, Xin Ding, Qi Zeng, Huafang Zou and Jianxiang Liao
    Citation: Acta Epileptologica 2022 4:6
    Content type: Case Report Published on:

  40. Super-refractory status epilepticus (SRSE) is a serious and life-threatening neurological condition. Ketogenic diet (KD) is a diet characterized by high fat, low carbohydrate, and moderate protein. As KD shows...

    Authors: Xin Tong, Qianyun Cai, Dezhi Cao, Lifei Yu, Dan Sun, Guang Yang, Jiwen Wang, Hua Li, Zengning Li, Juan Wang, Shaoping Huang, Meiping Ding, Fang Fang, Qun Wang, Rong Luo, Jianxiang Liao…
    Citation: Acta Epileptologica 2022 4:8
    Content type: Consensus Published on:

  41. Ketogenic diet (KD) therapy is one of the main treatments for drug-resistant epilepsy. However, the KD therapy has been applied in only a small number of infantile spasm cases. In this large multicenter study,...

    Authors: Yuanzhen Ye, Dan Sun, Hua Li, Jianmin Zhong, Rong Luo, Baomin Li, Dengna Zhu, Dan Li, Shaoping Huang, Yuwu Jiang, Nong Xiao, Yucai Chen, Yuqin Zhang, Mei Yu, Xiaoyun Shen, Li Gao…
    Citation: Acta Epileptologica 2022 4:11
    Content type: Research Published on:

    The Correction to this article has been published in Acta Epileptologica 2022 4:14

  42. There is no single way to improve epilepsy care in low- and middle-income countries (LMICs). An epilepsy management aid application (app) has been described, which enables a non-physician health worker (NPHW) ...

    Authors: Victor Patterson, Awais Bashir Larik, Mohamed Zaman Soomro and Steve Coates
    Citation: Acta Epileptologica 2022 4:12
    Content type: Research Published on:

  43. Epilepsy is the most common neurological disease in the world. The objective of the study was to determine the knowledge, attitude and practice of driver’s license applicants and instructors in driving schools...

    Authors: Dabilgou Alfred Anselme, Dravé Alassane, Kyelem Julie Marie Adeline, Eklou Lorrainda Emérance, Napon Christian, Millogo Athanase, Karfo Kapouni and Kaboré Jean
    Citation: Acta Epileptologica 2022 4:3
    Content type: Research Published on:

  44. Stroke is the most frequent cause of secondary epilepsy in the elderly. The incidence of cerebral stroke is increasing with the extension of life expectancy, and the prevalence of post-stroke epilepsy (PSE) is...

    Authors: Jiayu Chen, Haijiao Ye, Jie Zhang, Aihong Li and Yaohui Ni
    Citation: Acta Epileptologica 2022 4:2
    Content type: Review Published on:

  48. Posterior reversible encephalopathy syndrome (PRES) is a rare clinical disease that refers to the subcortical vasogenic edema involving bilateral parieto-occipital regions, with a usually reversible syndrome w...

    Authors: Lu Lu, Weixi Xiong, Yingying Zhang, Yingfeng Xiao and Dong Zhou
    Citation: Acta Epileptologica 2021 3:30
    Content type: Review Published on:

  49. High-frequency oscillations (HFOs) in the electroencephalography (EEG) have been extensively investigated as a potential biomarker of epileptogenic zones. The understanding of the role of HFOs in epilepsy has ...

    Authors: Yueqian Sun, Guoping Ren, Jiechuan Ren and Qun Wang
    Citation: Acta Epileptologica 2021 3:29
    Content type: Review Published on:
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