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  1. Acute symptomatic seizures are the main sign of neurological dysfunction in newborns. This is linked to the unique characteristics of the neonatal brain, making it hyperexcitable compared to older ages, and to...

    Authors: Carlotta Spagnoli and Francesco Pisani
    Citation: Acta Epileptologica 2024 6:5
  2. NR2F1 mutations are associated with Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Although ~ 46.7% of BBSOAS patients present with epilepsy, which is always drug-resistant and associated with higher rate...

    Authors: Xiao Li, Kai Gao, Yutang Li, Yuehua Zhang, Han Zhang and Yuwu Jiang
    Citation: Acta Epileptologica 2024 6:3
  3. The COVID-19 pandemic substantially increases the risk of severe psychological distress among people with epilepsy (PWE), especially those with monthly household income < 5000 RMB or with uncontrolled seizures...

    Authors: Xiaoting Hao, Qi Zhang, Chenxi Zhong, Enzhi Li, Yingqi Jiang, Jiajun Xu, Yuanyuan Li, Dong Zhou and Bo Yan
    Citation: Acta Epileptologica 2024 6:2
  4. Epilepsy is a common, long-term neurological condition. Several previous case-control, cohort and cross-sectional studies have highlighted the role of prenatal, delivery and postnatal factors in the onset of e...

    Authors: Imen Ketata, Emna Ellouz and Rahil Mizouri
    Citation: Acta Epileptologica 2024 6:1
  5. Although epilepsy has been acknowledged as an illness since ancient time, the public attitude toward epilepsy has not changed drastically due to the lack of appropriate information. This study aims to determin...

    Authors: Alawi A. Al-Attas, Omar K. Alshehri, Abdulrahman G. Malhan, Hani M. Alabdaly, Osamah K. Alfentokh and Amen A. Bawazir
    Citation: Acta Epileptologica 2023 5:30
  6. Epilepsy is a recurring neurological disease caused by the abnormal electrical activity in the brain. This disease has caused about 50 new cases in 100,000 populations every year with the clinical manifestatio...

    Authors: Komang Trisna Sumadewi, Saktivi Harkitasari and David Christopher Tjandra
    Citation: Acta Epileptologica 2023 5:28
  7. Developmental and epileptic encephalopathy (DEE) is a group of rare inherited disorders characterized by intellectual disability, delayed development, epileptic seizures, and other related symptoms. DEE44 is c...

    Authors: Suli Zhang, Shuangzhu Lin, Wanqi Wang, Yuru Gan, Cui Wang, Bangtao Li and Qiming Pang
    Citation: Acta Epileptologica 2023 5:27
  8. Epilepsy affects 50 million people worldwide. Nearly 80% of people with epilepsy live in resource-constrained low-income and middle-income countries. In Asia, which has a population of over 4 billion or has 50...

    Authors: Alhamdu Adamu, Rui Chen, An Li and Guofang Xue
    Citation: Acta Epileptologica 2023 5:25
  9. Smith-Kingsmore syndrome (SKS) is a rare autosomal dominant disorder caused by de novo mutations of gene MTOR in most cases and germline mosaicism in a few cases. The first case of SKS was reported in 2013. The i...

    Authors: Meiling Cai, Yanfei Zhao, He Wang, Shicheng Liu and Huiyi Jiang
    Citation: Acta Epileptologica 2023 5:24
  10. Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide. Drug-resistant epilepsy (DRE), status epilepticus (SE), and sudden unexpected death in epilepsy (SU...

    Authors: Yingchun Xu, Ge Tan, Deng Chen, Jiao Liu, Zixian Zhou and Ling Liu
    Citation: Acta Epileptologica 2023 5:23
  11. In the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures (ASs) may originate from a focal point and rapidly spread to the bilateral...

    Authors: Xiaoqin Sun, Miao Wang, Zeng He, Lihong Liu, Xianjun Shi, Chunqing Zhang, Ning An, Meihua Yang, Zhifeng Wu, Ruodan Wang, Li Wang, Zhongke Wang, Hui Yang, Xiaolin Yang and Shiyong Liu
    Citation: Acta Epileptologica 2023 5:22
  12. Anti-leucine-rich glioma-inactivated 1 (LGI-1) autoimmune encephalitis (AE), characterized by rapid decline of memory, seizures, and neuropsychiatric abnormalities, is a rare but devastating disorder. Early di...

    Authors: Emily Yixuan Huang, Hongfeng Gao and Ning Zhong
    Citation: Acta Epileptologica 2023 5:21
  13. Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy. Nonetheless, there is a substantial gap in the surgical treatment for appropriate candidates owing to...

    Authors: Lixin Cai, Kai Zhang, Wenjing Zhou, Xiaoqiu Shao, Yuguang Guan, Tao Yu, Ye Wu, Shuhua Chen, Rui Zhao, Shuli Liang, Xun Wu, Guoming Luan, Yuwu Jiang, Jianguo Zhang and Xiaoyan Liu
    Citation: Acta Epileptologica 2023 5:20
  14. Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a novel autoimmune encephalitis (AE) first identified in 2007. It provides a new direction for clinicians when encountering unexplained symptoms suc...

    Authors: Ningxiang Qin, Jing Wang, Xi Peng and Liang Wang
    Citation: Acta Epileptologica 2023 5:19
  15. Focal cortical dysplasia (FCD) is a common cause of drug-resistant epilepsy. Electroencephalography (EEG) biomarkers that predict good postoperative outcomes are essential for identifying patients with focal e...

    Authors: Sofía S. Sánchez-Boluarte, Wilfor Aguirre-Quispe, Manuel Herrera Aramburú, William O. Tatum and Walter De La Cruz Ramírez
    Citation: Acta Epileptologica 2023 5:18
  16. Recently, a novel workflow known as the virtual epileptic patient (VEP) has been proposed by a research team from Aix Marseille Université in their papers published in Lancet Neurology, Science Translational Medi...

    Authors: Qiao Wang, Guangyuan Jin, Tao Yu, Fabrice Bartolomei and Liankun Ren
    Citation: Acta Epileptologica 2023 5:17

    The Correction to this article has been published in Acta Epileptologica 2023 5:32

  17. Epilepsy is a neurological disease characterized by excessive and abnormal hyper-synchrony of electrical discharges of the brain and a predisposition to generate epileptic seizures resulting in a broad spectru...

    Authors: John Agbo, Zainab G. Ibrahim, Shehu Y. Magaji, Yahkub Babatunde Mutalub, Philemon Paul Mshelia and Daniel H. Mhyha
    Citation: Acta Epileptologica 2023 5:16
  18. In developing countries, there is a lack of epilepsy knowledge among health workers. The objective of this study was to assess the knowledge, attitude and practice concerning epilepsy among nurses and midwives...

    Authors: Alfred Anselme Dabilgou, Alassane Dravé, Julie Marie Adeline Wendlamita Kyelem, Fatimata Kinda, Christian Napon, Athanase Millogo and Jean Kaboré
    Citation: Acta Epileptologica 2023 5:12
  19. Hypothalamic hamartoma (HH) is a congenital non-progressive lesion of hypothalamus during fetal development. Mass-like lesions in different anatomical locations often develop a variously disabling course prese...

    Authors: Wenjie Han, Che Jiang, Zijuan Qi, Wei Xiang, Jian Lin, Youtian Zhou, Zhensheng Li and Bingmei Deng
    Citation: Acta Epileptologica 2023 5:11
  20. The genetic generalized epilepsies (GGEs) have been proved to generate from genetic impact by twin studies and family studies. The genetic mechanisms of generalized epilepsies are always updating over time. Al...

    Authors: Xiaoqian Wang, Xueyi Rao, Jia Zhang and Jing Gan
    Citation: Acta Epileptologica 2023 5:8
  21. Epilepsy is a common chronic neurological disease. Its repeated seizure attacks have a great negative impact on patients’ physical and mental health. The diagnosis of epilepsy mainly depends on electroencephal...

    Authors: Lijun Li, Hengxing Zhang, Xiaomei Liu, Jie Li, Lei Li, Dan Liu, Jieqing Min, Ping Zhu, Huan Xia, Shangkun Wang and Li Wang
    Citation: Acta Epileptologica 2023 5:7

    The Correction to this article has been published in Acta Epileptologica 2023 5:9

  22. SYNGAP1 is a significant genetic risk factor for global developmental delay, autism spectrum disorder, and epileptic encephalopathy. De novo loss-of-function variants in this gene cause a neurodevelopmental disor...

    Authors: Xingying Zeng, Yong Chen, Xiongying Yu, Yuanyuan Che, Hui Chen, Zhaoshi Yi, Jie Qin and Jianmin Zhong
    Citation: Acta Epileptologica 2023 5:6
  23. Hemispherectomy is an effective treatment option for patients with drug-resistant epilepsy caused by hemispheric lesions. However, patients often have deterioration of their motor functions postoperatively. Di...

    Authors: Huaqiang Zhang, Penghu Wei, Chao Lu, Zhenming Wang, Xiaotong Fan, Yongzhi Shan and Guoguang Zhao
    Citation: Acta Epileptologica 2023 5:2
  24. Migraine and epilepsy are both episodic disorders, with some overlapping symptoms, mechanisms and therapies. Clinically, there is a comorbid relationship between them. Some migraine patients may exhibit epilep...

    Authors: Yuting Yang, Xi Peng and Yangmei Chen
    Citation: Acta Epileptologica 2023 5:3
  25. Early diagnosis of medically intractable epilepsy is challenging in clinical work. P-glycoprotein (P-gp) is one of the most important multidrug efflux transporters, which has been demonstrated to contribute to...

    Authors: Yangmei Xie, Yiye Shao, Xue Gong, Ming Wang and Yinghui Chen
    Citation: Acta Epileptologica 2023 5:5
  26. Reflex seizures (RS) induced by micturition are extremely rare, and the clinical and electroencephalogram features of RS are not widely known among clinicians. In particular, the origin of the epileptic area i...

    Authors: Zhiyun Zhang, Qiwei Li, Tiejia Jiang and Jiajia Fang
    Citation: Acta Epileptologica 2023 5:4
  27. We have previously reported that hippocampal long-term potentiation (LTP) was suppressed in temporal lobe epilepsy (TLE) rats. The N-methyl-D-aspartic acid receptors containing 2B subunit (NR2B-NMDARs) are ind...

    Authors: Xiaoqing Luo, Cheng Li, Xiaoli Yu, Guangtao Kuang, Xiaolu Wang, Jufang Liang and Jun Jiang
    Citation: Acta Epileptologica 2023 5:1
  28. Lennox-gastaut syndrome (LGS) is an epileptic encephalopathy often associated with behavioral and psychiatric disorders. Vagus nerve stimulation (VNS) has been approved effective for LGS treatment. Surgical re...

    Authors: Renli Qi, Wei Wang, Yaoduan Xu, Zongling Shen, Xin Geng, Na Li, Jinghui Li and Hualin Yu
    Citation: Acta Epileptologica 2022 4:40
  29. Recent studies suggest potential roles of immune response in the pathophysiology of epilepsy. Anti-seizure medications (ASMs) are known to have side effects of drug eruption caused by immune responses. A few r...

    Authors: Takuji Nakamura, Keiko Uda, Muneaki Matsuo and Masafumi Zaitsu
    Citation: Acta Epileptologica 2022 4:36
  30. The KCNT1 gene encodes a Na+-activated K+ channel. Gain-of-function mutations of KCNT1 lead to autosomal dominant sleep-related hypermotor epilepsy, early-onset epileptic encephalopathy, focal epilepsy and other ...

    Authors: Meng Wang, Guifu Geng, Yao Meng, Hongwei Zhang, Zaifen Gao and Jianguo Shi
    Citation: Acta Epileptologica 2022 4:34
  31. Epilepsy affects over 70 million people worldwide; however, the underlying mechanisms remain unclear. MicroRNAs (miRNAs) have essential functions in epilepsy. miRNA-9, a brain-specific/enriched miRNA, plays a ...

    Authors: Shenglin Wang, Xuzhi He, Nana Bao, Mingyue Chen, Xiaomi Ding, Ming Zhang, Li Zhao, Shunxian Wang and Guohui Jiang
    Citation: Acta Epileptologica 2022 4:33
  32. Brain function is thought to rely on complex interactions of dynamic neural systems, which depend on the integrity of structural and functional networks. Focal epilepsy is considered to result from excessive f...

    Authors: Yanping Sun, Yuqiang Song, Hongjin Ren, Haifang Zhu, Yanning Wang, Xiaoli Li, Wenjing Yan and Yuping Wang
    Citation: Acta Epileptologica 2022 4:42
  33. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis accounts for the vast majority of cases of autoimmune encephalitis. Its common clinical symptoms are psychiatric symptoms, behavioral dysfunction, seizures,...

    Authors: Junjie Hu, Cailei Zhao, Xia Zhao, Yu Fang, Huiting Zhang, Dezhi Cao and Jianxiang Liao
    Citation: Acta Epileptologica 2022 4:30
  34. Posterior quadrant epilepsy (PCE) is a type of focal epilepsy that originates in the parietal lobe, occipital lobe, and the parietal-occipital border of the temporal lobe, or in any combination of these region...

    Authors: Mario Velasco, Andrés Felipe Cárdenas-Cruz, María Paula Aguilera-Pena, Alejandro Vargas-Moreno, Daniel Nariño, Juan Carlos Pérez and Oscar Zorro
    Citation: Acta Epileptologica 2022 4:27
  35. Vagus nerve stimulation (VNS) is an effective treatment for patients with refractory epilepsy, yet with varied predictive factors and heterogeneous long-term outcomes. Adjustment of VNS parameters is critical ...

    Authors: Cuiping Xu, Hua Lin, Jiwen Xu, Xiaohua Zhang, Guiliang Hao, Qiang Qiang Liu, Chengyun Ding, Shan Wang, Quanjun Zhao, Xiaojun Bai, Kui Chen, Duanyu Ni, Yongjie Li, Tao Yu and Yuping Wang
    Citation: Acta Epileptologica 2022 4:38
  36. Dravet syndrome (DS) is a severe epileptic encephalopathy in children dominated by polymorphic seizures. Focal cortical myoclonus indicated on conventional electroencephalogram (EEG) was rarely observed in DS.

    Authors: Xiaoqing Luo, Xiaolu Wang and Jun Jiang
    Citation: Acta Epileptologica 2022 4:13

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