Table 3 Evaluation of heterogeneity and pleiotropy using different methods
From: The impact of serum copper on the risk of epilepsy: a mendelian randomization study
Pleiotropy test | Heterogeneity test | |||||||
|---|---|---|---|---|---|---|---|---|
MR-Egger | MR-Egger | IVW | ||||||
Exposure | Outcome | Intercept | SE | P | Q | Q_pval | Q | Q_pval |
Serum copper | Epilepsy | -0.006 | 0.010 | 0.568 | 5.387 | 0.370 | 5.789 | 0.447 |
Generalized epilepsy | -0.026 | 0.017 | 0.190 | 4.150 | 0.528 | 6.453 | 0.374 | |
Focal epilepsy | -0.003 | 0.013 | 0.818 | 8.461 | 0.206 | 8.542 | 0.287 | |