Fig. 3
From: Gene variations of glutamate metabolism pathway and epilepsy
a-d EEG showed the electrical status epilepticus during slow-wave sleep (ESES) phenomenon during the interictal period when the patient was awake (a) and sleeping (b), before treatment. The ESES phenomenon disappeared after LEV treatment for two years, and only single sharp waves were recorded both in the awake (c) and sleeping (d) status. e Sanger sequencing verified the de novo GRIN2A gene truncation mutation c3074G>C(pSer1025*), as the parents were wild type at this site. f Brain MRI only showed vascular spaces in the centrum semiovale of both hemisphere, with no other structural lesions