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Fig. 3 | Acta Epileptologica

Fig. 3

From: Long non-coding RNA Tug1 regulates inflammation in microglia and in status epilepticus rats through the NF-κB signaling pathway

Fig. 3

Tug1 was downregulated in the LPS-treated microglia. a Phenotyping of microglial cells. The immunofluorescence showed positive expression of Iba1 and F4/80. b Western blotting analysis of IL-1β and TNF-α in rats at different LPS concentrations. c The mRNA expression of M1 type-associated markers CD11b, CD86, iNOS, IL-1β and TNF-α in microglial cells. d The mRNA expression of M2 type-associated markers CD32, CD163, Arginase-1, IL-4 and IL-10 in microglial cells. e The relative level of Tug1 in the LPS-treated microglia. f-g Pearson correlation analysis between Tug1 and TNF-α or IL-1β in the LPS-treated microglia. (*P < 0.05, **P < 0.01 vs Control)

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Acta Epileptologica

ISSN: 2524-4434

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