Table 1 Baseline characteristics of the patients at the time of KD initiation
Baseline characteristics | Patients at the time of KD initiation |
|---|---|
Age at epilepsy onset (months) Age at KD initiation (months) Duration of seizure onset to KD initiation (months) Number of AEDs failed before the initiation of KD | Mean:14.6, median: 6.0 [3.5-10.0] Mean:28.97, median:14.1 [9.5-44.0] Mean:14.4, median:8.1 [4.1-20.0] Mean:4.8 ± 1.8 |
Male/female (n) Global developmental delay (n,%) | 2.67:1 (40/15) 45, 81.8% |
Number of AED (n,%) | |
≤ 2 | 15, 27.3% |
> 2 | 40, 72.7% |
Number of seizure types (n,%) | |
1 | 25, 45.5% |
≥ 2 | 30, 54.5% |
Seizure frequency (n,%) | |
≤5/day | 17, 30.9% |
> 5/day | 38, 69.1% |
Etiology | |
Genetic (n,%) | 12, 21.8% |
Structural (n,%) | 26, 47.3% |
Unknown (n,%) | 17, 30.9% |
Electroclinical syndromes(41,74.5%) | |
West syndrome (n,%) | 32, 58.2% |
Dravet syndrome (n,%) | 3, 5.5% |
Lennox-Gastaut syndrome (n,%) | 2, 3.6% |
Ohtahara syndrome (n,%) | 2, 3.6% |
Doose syndrome (n,%) | 1, 1.8% |
Early myoclonic encephalopathy in infants (n,%) | 1, 1.8% |