Table 4 Demographic and clinical predictors of drug-resistance in univariate analysis
From: The long-term prognosis and predictors of epilepsy: a retrospective study in 820 patients
Variables | DRE n = 322 | Remission n = 388 | P-value |
|---|---|---|---|
Sex, male, n (%) | 174 (54.0) | 222 (57.2) | 0.396 |
Age at seizure onset, years, median (IQR; range) | 15 (10–25; < 1–70) | 15 (10–24; < 1–77) | 0.561 |
Age at seizure onset, ≤12 years, n (%) | 113 (35.1) | 140 (36.1) | 0.784 |
Seizure frequency at first arrival, ≥ 1 /month, n (%) | 242 (75.2) | 186 (47.9) | < 0.001 |
Number of AEDs at first arrival, n (%) | < 0.001 | ||
0 | 49 (15.2) | 155 (39.9) | |
1 | 134 (41.6) | 147 (37.9) | |
≥ 2 | 139 (43.2) | 86 (22.2) | |
Family history of epilepsy or FS, n (%) | 25 (7.8) | 34 (8.8) | 0.631 |
History of FS, n (%) | 28 (8.7) | 40 (10.3) | 0.467 |
EEG results at first arrival, n (%) | < 0.001 | ||
Normal | 47 (14.6) | 135 (34.8) | |
Epileptiform abnormality | 217 (67.4) | 199 (51.3) | |
Not available | 58 (18.9) | 54 (13.9) | |
MRI results, n (%) | < 0.001 | ||
Normal | 124 (38.5) | 227 (58.8) | |
Abnormal | 174 (54.0) | 129 (33.4) | |
Not available | 24 (7.5) | 30 (7.8) | |
Type of epilepsy, n (%) | < 0.001 | ||
Idiopathic | 27 (8.4) | 87 (22.4) | |
Symptomatic | 160 (49.7) | 100 (25.8) | |
Cryptogenic | 135 (41.9) | 201(51.8) | |
Observation time during study, years, median (IQR; range) | 3.5 (2.3–4.7; 1.0–10.6) | 3.6 (2.4–5.0; 1.0–12.3) | 0.175 |