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Table 1 Roles of TNFα in epilepsy

From: The role of the TNFα-mediated astrocyte signaling pathway in epilepsy

Function

Refs

Promote hyperexcitability via purinogenic signaling, glutamate release and modulation of neuronal transmitter release

[23]

Increase ictal discharges

[24]

Modulate glutamate receptor transport

[19]

Induce apoptosis

[25]