Table 2 The treatment and outcome of the patients
No. | Number of AEDs used before KD | Duration of SE before KD (d) | Day of blood BHB beyond 2 mmol/L after diet (d) | Highest level of blood BHB (mmol/L) in ICU | Day of SE controlled after KD (d) | Duration of KD use | Adverse reaction of KD | Duration of staying in ICU (d) | Time of seizure recurrence after KD | Seizure frequency after seizure recurrence | Intellectual disability | Brain MRI at 6 months follow-up | Number of AEDs used at 1 year follow up |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | 4 | 22 | 2 | 4.1 | 14 | 8 m | Urinary stones | 62 | 43 d | Daily seizures | Moderate | Mild general atrophy | 5 |
Case 2 | 4 | 12 | 3 | 2.6 | 7 | 12 m | No | 26 | No | No | No | Normal | No |
Case 3 | 4 | 8 | 1 | 3 | 15 | 27 d | Arrhythmia/Urinary stones | 32 | 4 m | Monthly seizures | Mild | Mild general atrophy | 4 |
Case 4 | 3 | 10 | 3 | 2.9 | No effect | 36 d | No | 82 | / | Daily seizures | Severe | Severe general atrophy | 4 |
Case 5 | 3 | 7 | 7 | 2.2 | 6 | 3 m | No | 29 | 20 d | Monthly seizures | Mild | Mild general atrophy | 4 |
Case 6 | 3 | 2 | 14 | 2.1 | 7 | 12 m | No | 26 | 5 m | weekly seizures | Mild | Mild general atrophy | 4 |
Case 7 | 3 | 6 | 6 | 4.1 | 8 | 3 m | No | 31 | 2 m | Monthly seizures | Mild | Mild general atrophy | 3 |
Case 8 | 2 | 6 | 12 | 0.9 | No effect | 8 d | Urinary stones/hematuresis | 83 | / | Daily seizures | Moderate | Moderate general atrophy | 4 |
Case 9 | 2 | 20 | 6 | 4.1 | 19 | 8 m | No | 53 | 15 d | weekly seizures | Mild | Mild general atrophy | 4 |
Case 10 | 4 | 20 | 10 | 2.9 | 2 | 8 m | No | 37 | 3 m | Semi-annually seizures | Mild | Mild general atrophy | 3 |