Fig. 2

Brain MRI, EEG and Sanger sequencing of patient 1. a Axial T2 flair images showed abnormal signals around bilateral lateral ventricles, multiple small polygyrus in double occipital lobes and obviously on the posterior horn of right lateral ventricle. b The boundary of he gray and white matter of the left parietal and temple lobe is unclear in sagittal position. c Scalp EEG. Medium- to high-amplitude, irregular sharp slow waves and spike slow waves can be seen in each lead of bilateral hemispheres during the interictal period. d Sanger sequencing  verified c970C > T de novo mutation of SLC1A2, while her parents were wild type at this site