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Table 4 Univariate analysis of factors affecting the response rate to KD

From: Efficacy and tolerability of ketogenic diet therapy in 55 Chinese children with drug-resistant epilepsy in Northwest China

Factor

Outcome

Test statistic

P value

Favorable

Unfavorable

Gender

 Male

24

16

χ2 = 0.199

P = 0.655

 Female

8

7

Age of seizure onset (months)

 Median

6.25[3.6–14.3]

6.0[3.4–8.1]

U = 326.0

P = 0.473

Age at KD initiation (months)

 Median

13.0[8.6–40.9]

19.3[10.8–45.5]

U = 291.5

P = 0.192

Duration of seizure onset to KD initiation (months)

≤6

  Yes

19

5

χ2 = 7.707

P = 0.006*

  No

13

18

  

≤12

  Yes

24

10

χ2 = 5.633

P = 0.018*

  No

8

13

Duration of KD retention (months)

  ≤6

6

12

χ2 = 6.79

P = 0.009*

  > 6

26

11

Number of AEDs at KD initiation

  ≤ 2

10

5

χ2 = 0.610

P = 0.435

  > 2

22

18

Number of seizure types

 1

13

12

χ2 = 0.720

P = 0.396

  ≥ 2

19

11

West syndrome

 Yes

19

1

χ2 = 0.045

P = 0.832

 No

13

10

  1. Univariate analysis Chi-Square test (χ2), Mann-Whitney U test, * level of significance p < 0.05