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Table 4 Univariate analysis of factors affecting the response rate to KD

From: Efficacy and tolerability of ketogenic diet therapy in 55 Chinese children with drug-resistant epilepsy in Northwest China

Factor Outcome Test statistic P value
Favorable Unfavorable
Gender
 Male 24 16 χ2 = 0.199 P = 0.655
 Female 8 7
Age of seizure onset (months)
 Median 6.25[3.6–14.3] 6.0[3.4–8.1] U = 326.0 P = 0.473
Age at KD initiation (months)
 Median 13.0[8.6–40.9] 19.3[10.8–45.5] U = 291.5 P = 0.192
Duration of seizure onset to KD initiation (months)
≤6
  Yes 19 5 χ2 = 7.707 P = 0.006*
  No 13 18   
≤12
  Yes 24 10 χ2 = 5.633 P = 0.018*
  No 8 13
Duration of KD retention (months)
  ≤6 6 12 χ2 = 6.79 P = 0.009*
  > 6 26 11
Number of AEDs at KD initiation
  ≤ 2 10 5 χ2 = 0.610 P = 0.435
  > 2 22 18
Number of seizure types
 1 13 12 χ2 = 0.720 P = 0.396
  ≥ 2 19 11
West syndrome
 Yes 19 1 χ2 = 0.045 P = 0.832
 No 13 10
  1. Univariate analysis Chi-Square test (χ2), Mann-Whitney U test, * level of significance p < 0.05