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Table 1 Two cases of anesthetics-induced epileptic seizures who had a history of epilepsy

From: Two cases of anesthetics-induced epileptic seizures: a case report and literature review

  Sex/ age History of epilepsy AEDs before surgery Seizure-free duration Surgery Anesthesia Epileptic seizure Treatment EEG CT/MRI AEDs after surgery One year follow-up
Case 1 Female/16 GTCS 13 years ago, lasting 1–2 min and repeated more than 10 times intermittently Sodium valproate and oxcarbazepine 3 years Rhinoplasty and double-eyelid surgery Propofol (100 mg) General anesthesia During surgery, the patient began to present with spasmodical convulsions, more prominent on the upper and lower extremities . Midazolam (10 mg) and Diazepam (20 mg) Normal Normal Oxcarbazepine (300 mg bid), Sodium valproate (500 mg bid) No seizure
Case 2 Female/34 Limb clonic seizures 5 years ago, lasting 2–4 min. This attack occurred 1–2 times a day, more frequently in the afternoon. Sodium valproate, oxcarbazepine, and lamotrigine 5 years Bilateral tonsillectomy Lidocaine (160 mg) Local anesthesia Immediately after local anesthesia, the patient suffered from a GTCS, which lasted for about 20 min. Diazepam (10 mg) Increase of slow waves in both hemispheres Slight enlargement of the left ventricle temporal horn Lamotrigine (75 mg bid), Sodium valproate (500 mg bid) No seizure
  1. AEDs Antiepileptic drugs, EEG Electroencephalography, CT Computed tomography, MRI Magnetic resonance imaging, GTCS Generalized tonic-clonic seizure