Table 1 Years of introduction in the market of currently available antiseizure medications. For all drugs, year of introduction refers to either Europe or the United States of America. The table does not include a number of drugs approved before 1970, but rarely used today
From: The pharmacological treatment of epilepsy: recent advances and future perspectives
1900–1950 | 1951–1985 | 1986–2000 | 2001–2015 | 2015–2021 |
|---|---|---|---|---|
Phenobarbital Phenytoin | Carbamazepine Clobazam Clonazepam Diazepam Ethosuximide Midazolam Primidone Valproic acid | Felbamate Fosphenytoin Gabapentin Lamotrigine Levetiracetam Lorazepam Oxcarbazepine Tiagabine Topiramate Vigabatrin Zonisamide | Eslicarbazepine acetate Lacosamide Perampanel Pregabalin Rufinamide Stiripentol | Brivaracetam Cannabidiol Cenobamate Everolimus Fenfluramine |