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Fig. 6 | Acta Epileptologica

Fig. 6

From: Linsitinib (OSI-906) modulates brain energy metabolism and seizure activity in the lithium-pilocarpine rat model

Fig. 6

Ultrastructural changes of nucleus and mitochondria in neurons. (a) Hippocampal neurons and mitochondria in control rats. (b) Ultrastructural changes of nuclei and mitochondria in hippocampal neurons. (c) Compared to the epilepsy model group, the 50 mg/kg OSI-906 group showed less damage to the mitochondria and nuclei. a, b and c are magnified 8,000 times, and a1, b1 and c1 are magnified 20,000 times

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