NO. | ASM before pregnancy | Seizure frequency before pregnancy | ASM changes in the 1st trimester | ASM changes in the 2nd trimester | ASM changes in the 3rd trimester | Seizure frequency change in the 1st trimester | Seizure frequency change in the 2nd trimester | Seizure frequency change in the 3rd trimester |
---|---|---|---|---|---|---|---|---|
1 | VPA | Yearly | Stop ASM | VPA resumed | Increased | Increased | ||
2 | PHT | Monthly | Stop ASM | PHT resumed | Increased | Increased | Increased | |
3 | CBZ | More than 1 year | ||||||
4 | LEV | Monthly | Stop ASM | LEV resumed | Increased | Increased | ||
5 | More than 1 year | |||||||
6 | OXC, LEV | Monthly | Decreased | Decreased | ||||
7 | More than 1 year | |||||||
8 | More than 1 year | |||||||
9 | LEV | Monthly | Stop ASM | Decreased | ||||
10 | TPM | More than 1 year | TPM dose decrease | |||||
11 | CBZ, LEV | Daily | Increased | Decreased | ||||
12 | CBZ, LEV | Daily | Increased | Decreased | ||||
13 | More than 1 year | Increased | ||||||
14 | LTG, LEV | Monthly | LTG dose increase | LEV dose increase | LTG dose increase | Increased | Increased | Increased |
15 | TPM, PHT | Monthly | PHT → LTG | TPM → LEV |