Table 2 Stratified analysis of GABRG2 rs211037 polymorphism on IGE
Variables | TT + CT vs CC | TT vs CT + CC | TT vs CC | CT vs CC | T vs C | |||||
|---|---|---|---|---|---|---|---|---|---|---|
OR (95%CI) | Phet | OR (95%CI) | Phet | OR (95%CI) | Phet | OR (95%CI) | Phet | OR (95%CI) | Phet | |
Total | 1.07 [0.84, 1.35] | 0.006 | 1.04 [0.72, 1.49] | 0.007 | 1.10 [0.73, 1.67] | 0.005 | 0.99 [0.84, 1.16] | 0.070 | 1.06 [0.87, 1.31] | < 0.001 |
Ethnicity | ||||||||||
 Asian | 1.04 [0.70, 1.55] | < 0.001 | 1.10 [0.69, 1.74] | 0.005 | 1.15 [0.65, 2.02] | 0.003 | 0.95 [0.67, 1.36] | 0.030 | 1.06 [0.77, 1.47] | < 0.001 |
 Healthy control | 1.15 [0.97, 1.38] | 0.250 | 1.11 [0.73, 1.68] | 0.003 | 1.16 [0.72, 1.87] | 0.004 | 1.12 [0.93, 1.36] | 0.240 | 1.10 [0.89, 1.35] | 0.003 |
 JME | 0.97 [0.47, 2.02] | 0.004 | 1.36 [0.86, 2.15] | 0.190 | 1.30 [0.61, 2.75] | 0.080 | 0.72 [0.36, 1.44] | 0.060 | 1.08 [0.57, 2.04] | < 0.001 |
 CAE | 1.42 [0.92, 2.20] | 0.470 | 1.05 [0.57, 1.94] | 0.400 | 1.30 [0.59, 2.86] | 0.520 | 1.49 [0.94, 2.37] | 0.590 | 1.23 [0.89, 1.69] | 0.630 |
 Children | 1.19 [0.76, 1.88] | 0.050 | 0.98 [0.44, 2.20] | 0.006 | 1.14 [0.40, 3.27] | 0.002 | 1.28 [0.96, 1.72] | 0.460 | 1.07 [0.68, 1.69] | < 0.001 |
 Drug resistance | 1.64 [0.87, 3.07] | 0.002 | 1.97 [0.57, 6.79] | 0.020 | 2.84 [0.61, 13.25] | 0.002 | 1.41 [0.84, 2.37] | 0.040 | 1.70 [0.93, 3.11] | < 0.001 |