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Table 3 Stratified analysis of the association between GABRG2 rs211037 polymorphism and FS

From: Association between GABRG2 rs211037 polymorphism and febrile seizures: a meta-analysis

Variable na TT + CT vs CC TT vs CT + CC TT vs CC CT vs CC T vs C
OR (95%CI) Phet OR (95%CI) Phet OR (95%CI) Phet OR (95%CI) Phet OR (95%CI) Phet
Total 12 0.95 (0.64, 1.41) < 0.001 0.82 (0.50, 1.32) < 0.001 0.76 (0.39,1.46) < 0.001 1.05 (0.76,1.44) 0.04 0.95 (0.69, 1.32) < 0.001
Ethnicity
Asian 5 0.70 (0.48, 1.02) 0.65 0.63 (0.45, 0.88) 0.19 0.56 (0.36,0.87) 0.5 0.79 (0.53, 1.18) 0.57 0.73 (0.59, 0.90) 0.34
Caucasian 3 1.76 (0.97, 3.17) 0.03 1.36 (0.35, 5.27) 0.02 1.73 (0.34,8.78) < 0.001 1.56 (1.14, 2.15) 0.27 1.57 (0.87, 2.83) 0.003
Healthy control
Yes 9 0.76 (0.51, 1.12) 0.03 0.59 (0.45, 0.77) 0.38 0.50 (0.35,0.71) 0.41 0.96 (0.75, 1.24) 0.13 0.79 (0.61, 1.02) 0.01
No 3 1.86 (0.78, 4.43) 0.02 1.52 (0.25, 9.11) 0.02 1.92 (0.22,16.68) 0.004 1.67 (1.07, 2.61) 0.2 1.66 (0.71, 3.88) 0.002
Matched controls
Yes 6 0.60 (0.43, 0.86) 0.2 0.56 (0.39, 0.80) 0.31 0.40 (0.25, 0.63) 0.41 0.71 (0.49, 1.04) 0.28 0.64 (0.52, 0.80) 0.23
No 6 1.35 (0.86, 2.11) 0.02 1.01 (0.43, 2.36) < 0.001 1.16 (0.41, 3.22) < 0.001 1.37 (1.05,1.78) 0.27 1.21 (0.77, 1.91) < 0.001
  1. CI confidence interval, OR odds ratio, Phet P value of Q test for heterogeneity test
  2. aNumber of datasets included in the meta-analysis