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Table 2 Clinical data of the seven patients

From: The clinical phenotypes and genetic characteristics of seven epilepsy patients related to heterozygous DEPDC5 variants in China

No

Sex

Age of onset

Duration of epilepsy

Seizure type

Diagnose

EEG

MRI

Treatment

Prognosis

1

F

4

10

Focal onset, impaired awareness, hyperkinetic automatism, focal to bilateral tonic-clonic seizure

FLE

Lt ea

Normal

TPM, CZP, CBZ, LEV, LCM

refractory epilepsy

2

M

1

19

Focal onset, impaired awareness, behavior arrest, focal to bilateral tonic-clonic seizure

F-TLE

Bt ea

Normal

LTG, LEV

seizure freedom

3

M

8

18

Focal onset, focal to bilateral tonic-clonic seizure

TLE

Lt ea

Left HS

CBZ

seizure freedom

4

M

20

1

Focal onset, impaired awareness, behavior arrest, focal to bilateral tonic-clonic seizure

FLE

Lt ea

Normal

OXC, LEV

seizure freedom

5

M

2

9

Focal onset, impaired awareness, hyperkinetic automatism, focal to bilateral tonic-clonic seizure

FLE

Rt ea

Bilateral paraventricular white matter demyelination

OXC

relapse

6

F

12

12

Focal onset, without impaired awareness, clonic seizure

unspecified focal epilepsy

Normal

left paraventricular focal cortical dysplasia

LEV, OXC

effectiveness

7

F

10

11

Focal onset, focal to bilateral tonic-clonic seizure

FLE

Bt ea

Normal

LTG, LEV

effectiveness

  1. FLE Frontal lobe epilepsy, F-TLE Frontotemporal lobe epilepsy, TLE Temporal lobe epilepsy, Lt Left, Rt Right, Bt Bilateral, TPM Topiramate, CZP Clonazepam, CBZ Carbamazepine, LCM Lacosamide, LEV Levetiracetam, LTG Lamotrigine, OXC Oxcarbazepine