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Table 2 Clinical data of the seven patients

From: The clinical phenotypes and genetic characteristics of seven epilepsy patients related to heterozygous DEPDC5 variants in China

NoSexAge of onsetDuration of epilepsySeizure typeDiagnoseEEGMRITreatmentPrognosis
1F410Focal onset, impaired awareness, hyperkinetic automatism, focal to bilateral tonic-clonic seizureFLELt eaNormalTPM, CZP, CBZ, LEV, LCMrefractory epilepsy
2M119Focal onset, impaired awareness, behavior arrest, focal to bilateral tonic-clonic seizureF-TLEBt eaNormalLTG, LEVseizure freedom
3M818Focal onset, focal to bilateral tonic-clonic seizureTLELt eaLeft HSCBZseizure freedom
4M201Focal onset, impaired awareness, behavior arrest, focal to bilateral tonic-clonic seizureFLELt eaNormalOXC, LEVseizure freedom
5M29Focal onset, impaired awareness, hyperkinetic automatism, focal to bilateral tonic-clonic seizureFLERt eaBilateral paraventricular white matter demyelinationOXCrelapse
6F1212Focal onset, without impaired awareness, clonic seizureunspecified focal epilepsyNormalleft paraventricular focal cortical dysplasiaLEV, OXCeffectiveness
7F1011Focal onset, focal to bilateral tonic-clonic seizureFLEBt eaNormalLTG, LEVeffectiveness
  1. FLE Frontal lobe epilepsy, F-TLE Frontotemporal lobe epilepsy, TLE Temporal lobe epilepsy, Lt Left, Rt Right, Bt Bilateral, TPM Topiramate, CZP Clonazepam, CBZ Carbamazepine, LCM Lacosamide, LEV Levetiracetam, LTG Lamotrigine, OXC Oxcarbazepine