Fig. 1

Time-dependent decline in cognitive function in TLE rats. The mean escape latencies and the mean distance travelled at weeks 1 (a, d), 5 (b, e) and 13 (c, f) after induction of SE. g The time spent in the target quadrant in the control and TLE groups at weeks 1, 5 and 13 after induction of SE. h The step-through latency in the control and TLE groups at weeks 1, 5 and 13 after induction of SE. n=6 in each group; *: p<0.05, compared with controls. TLE: temporal lobe epilepsy; SE: status epilepticus