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Table 1 Basic data of patients

From: Bilateral asymmetric tonic seizure in insulo-opercular epilepsy: an anatomo-electro-clinical study

Patient No

Age of surgery (years)

Gender

Age of onset (years)

Duration (years)

VEEG-IID

MRI

PET hypometabolism regions

Total number of electrode

Total number of electrodes covering INS + OP

Total number of electrodes covering OP

Total number of electrodes exploring SMA/MCC

Resection/RFHC structure

Pathology

Follow-Up time (months)/ Engel level

1

22

M

12

10

Diffuse SW, temporal prominent

Malacia in Lt parasylvian+INS, Cop+Pop+Top+INSp prominent

Lt INSa+INSp+OFC + Fop + Cop+Pop+ Top+MTS + SMA + preSMA+MCC + NTL

Lt15,Rt2

Lt5,Rt2

Lt1

0/Lt1

Lt INS + Cop

Malacia, gliosis

36/ I

2

10

M

3

7

Diffuse SW, Lt hemisphere prominent

Lt INS + Cop FCD

Lt INSp+Cop+Pop+SMA + SPL

Lt8

Lt5

Lt1

Lt1/Lt1

Lt INS

FCDIb

51/ I

3

22

M

5

17

F7,F3 SW

Negative

Bil INSa(Lt > Rt) + INSp+Fop(Rt > Lt) + Cop+Pop(Rt > Lt) + SMA + preSMA+MCC

Lt13,Rt3

Lt5,Rt1

0

Lt1,Rt1/Lt1

Lt INS (residual cortex of both ends of ils and asg)

FCD Ib

31/ I

4

16

M

0.6

15.5

Diffuse SW, Lt temporal prominent

Lt INSp FCD

Bil INSa(Lt > Rt), Lt INSp+OFC + Fop, Bil Cop(Lt > Rt), Lt Pop+Top+MTS, Bil SMA(Lt > Rt) + MCC(Lt > Rt)

Lt11

Lt6

Lt1

Lt1/0

Lt INSp+Cop+Pop+post. Top

FCDIIa

27/II

5

7

M

5

2

Rt hemisphere SW, F4-C4 prominent

Rt INS FCD, psg + alg + Cop+Pop prominent.

Bil INSa+INSp(Rt > Lt) + Fop(Rt > Lt) + Cop(Rt > Lt) + SMA(Rt > Lt) + MCC(Rt > Lt)

Rt10

Rt4

0

Rt1/Rt1

Rt INSp+Cop+Pop

FCDIIa

27/I

6

4

M

0.7

3.3

Diffuse SW, F4, F8, Cz prominent

Rt TP + STG + INSp+Pop FCD

Rt INSa+OFC, Bil Fop(Rt > Lt), Rt Cop+Pop+Top+ MTS + SMA + preSMA+MCC + ACC + NTL

Rt12

Rt4

Rt2

Rt1/Rt2

Rt inf.INSa+INSp+ Pop+TP

FCDIIa

26/ I

7

6

F

2.5

2.5

Sagittal,parasagittal SW

Lt INS + Fop + Cop+Pop FCD

Bil INSa(Lt > Rt) + INSp(Lt > Rt) + Fop(Lt > Rt) + Cop(Lt > Rt), Lt Pop+Top, Bil SMA(Lt > Rt) + MCC(Lt > Rt) + ACC(Lt > Rt)

Lt11,Rt2

Lt5,Rt1

Lt1

Lt1/Lt1,Rt1

Lt INS + ant.Cop

Nonspecific change

12/III

8

17

M

4

13

Diffuse SW, Lt parasagittal prominent

Negative

Bil INSa(Lt > Rt), Lt OFC + Fop, Bil Cop, Lt Top+SMA

Lt10 + 4a

Lt3

Lt3

Lt2/Lt1

RFTC: bottom of Lt ds and IFS junction

7/ I

  1. afor twice implantation. M male, F female, Lt left, Rt right, Bil bilateral, ant. anterior, post. posterior, inf. inferior, SW spikes and waves, SMA supplementary sensorimotor area, pre-SMA pre-supplementary sensorimotor area, INS insula, INSa anterior part of insula, INSp posterior part of insula, alg anterior long gyrus of insula, asg anterior short gyrus of insula, psg posterior short gyrus of insula, ils inferior limiting sulcus, OP operculum, Fop frontal operculum, Cop central operculum, Pop parietal operculum, Top temporal operculum, MCC middle part of cingular cortex, ACC anterior part of cingular cortex, MTS mesial temporal structures, NTL neocortex of temporal lobe, TP temporal pole, SPL superior parietal lobue, OFC orbital frontal cortex, ds diagonal sulcus, IFS inferior frontal sulcus, RFTC stereotactic radiofrequency thermocoagulation