Table 3 Functional roles of the 5 hub genes
No. | Gene symbol | Full name | Functions of encoded protein |
|---|---|---|---|
1 | SNAP25 | Synaptosome Associated Protein 25 | Participates in the synaptic function of specific neuronal systems. |
2 | SLC32A1 | Solute Carrier Family 32 Member 1 | Involved in the uptake of GABA and glycine into the synaptic vesicles. |
3 | SYN1 | Synapsin I | Functions in the regulation of neurotransmitter release. |
4 | GRIN1 | Glutamate Ionotropic Receptor NMDA Type Subunit 1 | A component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels. |
5 | GRIA1 | Glutamate Ionotropic Receptor AMPA Type Subunit 1 | An ionotropic glutamate receptor, which facilitates excitatory neurotransmitter transport at many synapses in the central nervous system. |