Table 2 Potential anti-inflammatory effects of anti-epileptic drugs
Drug | Inflammatory effect | Reference |
|---|---|---|
Valproate | Inhibit NF-κB and then decrease levels of TNF-α and IL-16 of monocytes and glia. | [177] |
Carbamazepine | Increase the cytotoxic activity of NK cells. | [177] |
Phenytoin | Decrease the number of suppressor T cells, and reversibly decrease IgA. | [177] |
Vigabatrin | Increase the cytotoxic activity of NK cells. | [177] |
Levetiracetam | Reduce reactive gliosis and expression of IL-1β. | [177] |
Diazepam | Inhibit human T cell function and decrease IFN-γ production. | [177] |