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Table 2 Potential anti-inflammatory effects of anti-epileptic drugs

From: The role of inflammation in epileptogenesis

Drug Inflammatory effect Reference
Valproate Inhibit NF-κB and then decrease levels of TNF-α and IL-16 of monocytes and glia. [177]
Carbamazepine Increase the cytotoxic activity of NK cells. [177]
Phenytoin Decrease the number of suppressor T cells, and reversibly decrease IgA. [177]
Vigabatrin Increase the cytotoxic activity of NK cells. [177]
Levetiracetam Reduce reactive gliosis and expression of IL-1β. [177]
Diazepam Inhibit human T cell function and decrease IFN-γ production. [177]