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Table 3 Key-points of practical management (positive and severity diagnoses) according to the scenario

From: The first-line management of psychogenic non-epileptic seizures (PNES) in adults in the emergency: a practical approach

 

First suspicious episode (s)

Previous similar episodes

Diagnosed epilepsy (unknown PNES)

Known PNES diagnosis

PNES status

History key-points

- Details suggestive of PNES?

- Psychic bases?

- Diagnostic score

- Prior semiology (also possible ES?)

- Psychic bases?

- Diagnostic score

- Define the bases of the previous ES diagnosis (clinical? iiEEG? iEEG?)

- Unusual semiology?

- Frequency? AED?

- Recurrence circumstances

- Major psychiatric disorders (especially suicidal risk)?

- Recent social situation of the patient

- Known epilepsy?

Physical examination

- Amateur video

- Induction test

- Amateur video

- Induction test

- Amateur video

- Induction test

- Depression diagnostic score if possible

- Inhibition test

Early paraclinical investigations

- Bedside EEG if possible

- Prolactin level within 10–20 min if possible FBTCS

- Bedside EEG if chances of in-hospital recurrences

- Prolactin level within 10–20 min if possible FBTCS

- Bedside EEG if chances of in-hospital recurrences

- Prolactin dosage within 10–20 min if possible FBTCS

- Not a must

- Prolactin dosage within 10–20 min (maximum of 30 min) if possible FBTCS

- Prolactin dosage (interpretation with caution after the first hour)

- Bedside EEG

Referrals and deferred tests

- Routine EEG as outpatient

- Neurology referral

- Systematic routine EEG as outpatient

- Neurology referral

- Neurology referral

- Neurology referral

- Neurology referral

  1. FBTCS bilateral tonic-clonic seizure, ES epileptic seizure, PNES psychogenic non-epileptic seizure, iEEG ictal electroencephalography, iiEEG interictal electroencephalography, AED antiepileptic drugs