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Fig. 3 | Acta Epileptologica

Fig. 3

From: SiRNA-mediated ankyrin-G silence modulates the expression of voltage-gated Na channels in murine hippocampal HT22 cells

Fig. 3

Immunocellularchemistry assay for Ankyrin-G, Nav1.6 and Nav1.1 after siRNA interference in HT22 cells. In the representative sections, antibodies illustrate the localizing of Ankyrin-G, Nav1.6 and Nav1.1 labeled with Alexa555 in red and nuclei were revealed by Hoechst in blue. Quantification of Ankyrin-G revealed significant decrease of normalized integrated density after siRNA silence compared to NC group (P < 0.05). Similar change of integrated density of Nav1.6 were detected (P < 0.05)

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