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Table 1 Demographic information for subjects with intractable focal epilepsy

From: Systemic evidence of acute seizure-associated elevation in serum neuronal injury biomarker in patients with temporal lobe epilepsy

Study ID Agea Sex Ethnicity Primary diagnosisb Disease onsetc Disease durationd MTSe
E001 30–35 F White
Not Hispanic / Latino
Intractable focal epilepsy;
temporal lobe epilepsy;
prior history of L temporal lobectomy (2012)
8 YO 23 y L MTS by pathology
E002 25–30 M White
Not Hispanic / Latino
Intractable focal epilepsy;
temporal lobe epilepsy;
history of febrile illness-associated encephalitis
25 YO 5 m MRI evidence of bilateral MTS
E003 45–50 F White
Not Hispanic / Latino
Intractable focal epilepsy;
temporal lobe epilepsy
17 YO 32 y No evidence of MTS on MRI
E004 40–45 M White
Not Hispanic / Latino
Intractable focal epilepsy;
temporal lobe epilepsy;
remote history of prior R temporal lobectomy (2001);
right parietal lobectomy (2016)
1 YO 41 y R parietal lobe sclerosis and neuronal karyorrhexis by pathology
E005 30–35 F White
Not Hispanic / Latino
Intractable focal epilepsy; temporal lobe epilepsy;
remote history of severe limbic encephalitis
24 YO 9 y MRI evidence of bilateral MTS
E006 35–40 F White
Not Hispanic / Latino
Intractable focal epilepsy;
temporal lobe epilepsy
14 YO 24 y No evidence of MTS
E007 40–45 M White
Not Hispanic / Latino
Intractable focal epilepsy; temporal lobe epilepsy;
prior history of R anterior temporal lobectomy (2008)
6 MO 29 y R MTS by pathology
  1. aAge at time of enrollment (in years); range provided for anonymization
  2. bL left, R right
  3. cYO years old, MO months old
  4. dDisease duration at time of enrollment; y years, m months
  5. eMTS mesial temporal sclerosis; changes on MRI (hippocampal atropy and increased T2 signal) or pathological diagnosis